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This calculator calculates the approximate equivalence among distinct benzodiazepine derivatives. Benzo dosage equivalence is just not a hard science — there is limited proof out there inside the study to match benzodiazepine equivalence. This calculator is based on out there dosage information for each drug coupled with professional opinion.

Delorazepam (Dadumir) is sold in Italy with the procedure of anxiety and sleeplessness. It’s among the list of several In a natural way-happening benzodiazepines and is surprisingly powerful. This compound is roughly 10 occasions as strong as diazepam and has a superior bioavailability of nearly eighty%. 

Following day drowsiness and "hangover effect" is a concern with benzodiazepines which have a long duration, for example, with diazepam or flurazepam.

All benzodiazepines are listed as DEA routine IV managed substances. As managed substances, all benzodiazepines have the probable for abuse, dependancy and diversion.

Phenazepam was the very first designer benzodiazepine (DBZD) to enter the industry. This compound has been on the market given that not less than 2007 but is considered to have already been developed from the Soviet Union during the 1970s. 

Lofendazam is carefully relevant to clobazam, and one of its Energetic metabolites, arfendazam. Not A great deal is thought about this drug in terms of security and effects, and there are no pharmaceutical companies at the moment offering this medication.

Benzodiazepines are not appropriate for the long-term Charge of epilepsy because of the event of tolerance in a higher proportion of patients.

There are some experiences this drug was utilized by the US army to assist soldiers fall asleep through challenging or stressful conditions. 

This atypical benzodiazepine doesn’t bind to GABA and subsequently doesn’t generate any with the attribute hypnotic effects of other benzodiazepines.

This drug is incredibly long-lasting — the elimination 50 percent-life of medazepam ranges from 36 to 200 several hours — Therefore the effects can very last anywhere from a full working day to 3 days in individuals with slower section I and II liver metabolism. 

Vital: A lot of drug interactions can happen with benzodiazepines. An evaluation of all medicines for drug interactions needs to be done by a healthcare company every time a different drug is additional or discontinued in almost any treatment method program.

Pyrazolam shares similarities to alprazolam and bromazepam. Much like these Benzodiazepines for anxiety other drugs, pyrazolam is notoriously powerful. 

Clonazepam is accessible as Klonopin, Klonopin ODT, and generic clonazepam in the following dosage types which can be taken by mouth.